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Mechanism of Allosteric Modulation of Nicotinamide Phosphoribosyltransferase to Elevate Cellular NAD.
Biochemistry. 2023 Feb 21;62(4):923-933. doi: 10.1021/acs.biochem.2c00655. Epub 2023 Feb 6.
Biochemistry. 2023.
PMID: 36746631
Free PMC article.
Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs).
Shen Z, Ratia K, Krider I, Ackerman-Berrier M, Penton C, Musku SR, Gordon-Blake JM, Laham MS, Christie N, Ma N, Fu J, Xiong R, Courey JM, Velma GR, Thatcher GRJ.
Shen Z, et al. Among authors: musku sr.
J Med Chem. 2023 Dec 28;66(24):16704-16727. doi: 10.1021/acs.jmedchem.3c01406. Epub 2023 Dec 14.
J Med Chem. 2023.
PMID: 38096366
Free article.
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Nicotinamide Phosphoribosyltransferase Positive Allosteric Modulators Attenuate Neuronal Oxidative Stress.
Gordon-Blake J, Ratia K, Weidig V, Velma GR, Ackerman-Berrier M, Penton C, Musku SR, Alves ETM, Driver T, Tai L, Thatcher GRJ.
Gordon-Blake J, et al. Among authors: musku sr.
ACS Med Chem Lett. 2024 Jan 24;15(2):205-214. doi: 10.1021/acsmedchemlett.3c00391. eCollection 2024 Feb 8.
ACS Med Chem Lett. 2024.
PMID: 38352833
Free PMC article.
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